FINALLY… Free Yourself from IBS In Only 28 Days, Even If You’ve Been Told to Just ‘Live With It’
April 7th 2021
by: Vincent Pedre M.D.
Irritable bowel syndrome (IBS) is the most common gastrointestinal disease in the world, with a prevalence of about 15 percent. That means one out of seven people will be diagnosed with IBS at some point in their lives.

I was one of them. Plagued by digestive issues for the greater part of my teenage years, as well as my 20’s and 30’s, I sought to find the answer to something that Western medicine did not believe to be curable. After twenty plus rounds of antibiotics as a teenager, my gut was a mess, and it took me the greater part of two decades to finally heal it. Unfortunately, there are still too many people suffering from IBS.

I mean, one out of seven people is about 1.7 billion people worldwide…that’s a lot, isn’t it? And it’s really grown in the last two decades. What explains the high prevalence of this digestive disease?

What We’re Getting Wrong About IBS

The answer lies in changes in our food supply, processed food, genetically modified crops, chronic stress, gastrointestinal infections, and the overprescribing of antibiotics. All these factors together have sabotaged our gut health and contributed to the huge increase of very real digestive symptoms like chronic constipation, diarrhea, excessive bloating, and stomach pain.

And here’s where the problem gets even deeper: The medical community uses “IBS” as an umbrella diagnosis, which means a person is diagnosed with it when they experience chronic gastrointestinal symptoms without a clear structural or functional reason. Conventional medicine diagnoses IBS using the Rome Criteria, which have defined IBS as:

“Recurrent abdominal pain, on average, at least 1 day/week in the last 3 months, associated with two or more of the following criteria:

  • related to bowel movements
  • associated with a change in the frequency of stools
  • associated with a change in form (appearance) of stool

And these criteria must be fulfilled for the last 3 months with symptom onset at least 6 months before diagnosis.”

The Problem: It’s just describing symptoms. What’s the root cause?!

If you think this sounds pretty broad, that’s because it is. If you have digestive issues but your doctor can’t immediately figure out why, or diagnose you with a known issue like Crohn’s, then they label you as having “IBS.” You’ll notice that the definition above has everything to do with the symptoms you experience and how frequently you experience them — it has nothing to do with the actual underlying cause of the issue or even the specific symptoms themselves. And because we don’t understand the underlying cause, there is currently no diagnostic test for IBS. After all, what would you test for if you don’t know what to look for? The only tests they run are to rule out other conditions.

If you’re like me, you’ll read the section above and ask yourself: There must be a better way, right? Actually, there is. Keep reading to learn about the HAPPY GUT® ‘blueprint’ — my approach to irritable bowel syndrome.

The HAPPY GUT® Approach to IBS

The Western model for IBS is simply wrong. For one, it clumps the millions of people walking around with completely different gut health symptoms — some with chronic diarrhea, constipation, others with cramping, and some with GERD or reflux — into the same diagnosis. The standard medical approach to IBS also neglects to uncover what the underlying cause of IBS really is; instead, your doctor will focus on relieving symptoms with drugs like laxatives, antidiarrheal medications, antacids, or even antidepressants. And while relief from painful and uncomfortable symptoms is always welcome, it doesn’t help get to the root of the problem, which means you’ll inevitably have more problems down the line and need more or different medications. Oftentimes, the very meds used to treat IBS have other, unwelcome side-effects or consequences.
Instead, why not take the time to look at IBS from a systems biology perspective? That means that instead of focusing on the smaller pieces of IBS — like the symptoms and medications — we try to put all the pieces together to understand the big picture of digestive health.

This is exactly what I did in my book Happy Gut and it’s what I’m going to teach you to do today. If you want to tame IBS, you need to zoom out and look at the gut as a whole, then zoom back in and look at that secret world inside you — your gut microbiome.

The 3 Components of a Healthy Gut

If you have IBS, it’s tempting to focus on the symptoms you’re experiencing — which are very real and difficult to cope with — and find the quick fix solution for them. But I actually challenge my patients to focus on what makes a gut healthy first; that way, we can identify what’s going wrong and how we can fix it, not just for a day or a few months, but for life.

For a healthy, happy gut, we have to look at these three key components:

1. The Gut Microbiome

The gut microbiome is the community of at least 100 trillion bacteria living mainly in your large intestine. The vast majority of these bacteria are good; in fact, humans have evolved alongside these microbes to the point where we’ve developed a very symbiotic relationship with them. For example, the good bacteria in our gut feed off the foods we eat and in turn, they help us by making vitamins, short-chain fatty acids, and neurotransmitters like serotonin — a chemical that makes us feel happy. They also help us absorb and break down nutrients and regulate our immune system. And they do this while crowding out bad bugs from overgrowing in the gut.

Pretty great, right?

Unfortunately, a combination of a low-fiber, high-sugar diet, stress, medications, antibiotics, lack of exercise, and environmental factors can sabotage the delicate balance of bacteria in our guts and by doing so, it creates damaging ripple effects throughout the entire body, affecting our health.

If you have IBS, you almost definitely have an imbalance in gut bacteria. In fact, studies have shown that 73% of IBS patients have dysbiosis (an imbalance between good and bad bugs, tipped in the favor of the bad). A large chunk of people also develop IBS after an infection of pathogenic bacteria like E. Coli, Salmonella, or Campylobacter jejuni, which disrupt the balance. According to new research, these pathogenic bacteria can produce toxins called cytolethal distending toxins (CDTs for short), which seem to play a major role in IBS that we haven’t been aware of until now. In fact, CDT’s can trigger an immune response in the gut, including antibodies to the very proteins that hold gut cells together, possibly triggering an autoimmune attack. This new information suggests that for some people, chronic IBS may actually be an autoimmune condition.


The bottom line:

Addressing microbiome imbalances is an absolutely critical part of tackling the underlying causes of your gut distress.

2. The Gut Lining

Your gut lining is another important element of healthy digestion. This one-cell-layer-thick lining is responsible for absorbing nutrients and keeping other harmful things — like large, partially-digested food particles, toxins, and pathogenic microbes — out of the bloodstream where they can wreak havoc by triggering an immune response that leads to inflammation. Unfortunately, an imbalance in the gut microbiome can lead to a breakdown in tight junction proteins — which are like the security guards who decide what passes through and what stays out. This can lead to a leaky gut, which allows food particles, microbes, and microbial toxins (like endotoxin) to slip through the gut lining and causes inflammation, food allergies and sensitivities, and all types of digestive symptoms.

New research on CDTs (I mentioned above) has shown that these toxins can also cause increased permeability in the gut lining. But here’s the interesting part: CDTs can cause leaky gut without actually harming the tight junction proteins, which means they cause a new, sneaky type of leaky gut. There’s even a new line of research exploring whether these CDTs can bind to the body’s proteins and cause the immune system to attack itself. This means that in the near future, IBS might be described as an autoimmune issue. This is a totally new way to look at what actually causes the disease. The new things we’re learning about CDTs mean that we’re also one big step closer to developing a simple test for this subset of IBS.


The bottom line:

We’re learning more every day about how digestion and the immune system is impacted by leaky gut, including new mechanisms by which leaky gut can exist. Healing leaky gut is a key component of healing the root causes of IBS.

3. The Whole Gut

As you’re probably already sensing from reading the first two components of a healthy and happy gut, the gut is an amazingly complex part of the body. It’s no wonder so much can go wrong with it! Understanding IBS requires us to zoom out and look at the full picture of the gut and all its many mechanisms. In order for you to digest properly, your gut has to move at a pace that allows you to have regular bowel movements, which require plenty of water and fiber in your diet. You also have to produce bile salts to emulsify and absorb fats, as well as adequate amounts of digestive enzymes, which are produced by both your pancreas and the cells that line the gut lining, and adequate stomach acid to break down the foods you eat. This is something that can easily get interrupted by a stressful day (stress has been linked to decreased HCL production). If you’ve ever had stomach ache after a stressful meal, you’ve experienced this connection first hand!

The other thing that’s consistently underestimated are the wide-ranging effects of IBS, which can impact so many other areas of your life — like your concentration, mood, and energy levels. The gut is the cornerstone of your health; it impacts your immune system, the production of your brain’s “happy chemicals” and can either help or hurt your metabolism and energy levels.


The bottom line:

When looking at IBS, you have to consider how it affects the body as a whole. Start by supporting the functioning of the digestive system as a whole, from enzyme production to the rhythmic contractions of the intestines.

5 Steps to Beat the Bloat, Improve Mental Clarity, and Boost Energy

As we already know, treating IBS isn’t just about covering up constipation, diarrhea, or digestive symptoms. It’s also about investing in the three components of a healthy gut as well as getting other symptoms like brain fog and fatigue under control. figured it out for myself after over two decades of suffering unpredictable abdominal pain, mental fog, fatigue, and skin rashes. And I’ve worked with hundreds of patients, helping them navigate their own gut-healing journeys.

So how do I do it? I follow…

The 5 Steps of the HAPPY GUT®



CLEANSE: This step involves removing common gut irritants, like gluten, sugar, and lectins, and toxins from foods. This will help you shed unwanted weight, get your energy back, and give you some relief from distressing digestive symptoms like bloating and diarrhea.


ACTIVATE: This step is all about replacing essential nutrients and enzymes, especially ones that are known to reactivate healthy digestion. That way, you can have free and easy digestion without the bloating and irritated stomach.


RESTORE: This step is all about reintroducing beneficial bacteria, using prebiotic foods and probiotic supplements. That way, you’re working with a healthy gut flora and can recover from any previous GI infections or imbalances. Once you’ve done that, your stomach can return to doing its job quietly, without talking back to you.


ENHANCE: This step is all about repairing the gut lining we’ve just learned so much about. This is the step that takes the most time and patience. You’ll get there with perseverance. Reversing a leaky gut requires your body to heal on a deep level; that way, you can turn back the clock on chronic disease and restore balance to your immune system.


SUSTAIN: Finally, this last step is about finding a lifestyle plan that helps you sustain all of the progress you’ve made. That means stress management, great hydration practices, and avoiding gut irritants, like pesticides and antibiotics, as much as possible so you don’t develop dysbiosis again in the future.

The good news is I’ve simplified all of this into one program that has helped thousands of people conquer their gut and gut-related health issues for good — my HAPPY GUT® REBOOT: 28-Day Cleanse. This program is based on the Blueprint above. In just 28 days, you can complete the 5 steps to heal your IBS by working on the root causes to free yourself from chronic medications that only treat symptoms.

Here’s what people have to say about it:

“About a year ago my digestion suddenly changed for the worse and I would regularly have floating stools, horrible nausea, and a dull pain in my upper left abdomen. Almost anything I would eat would trigger these symptoms.

However, I am pleased to say that after following your diet in the book for a couple of months i am feeling much much better. My digestive system is better than it has been in years. The pain seems to have gone as well. My energy is improving as well.”

– David

“Currently on Day 6 of [the] Happy Gut [Reboot]! Loving the app! So far it already feels like I have reduced inflammation and my mood and energy is up!!”

– Shelley

Instead of putting a BAND-AID over the issue, the HAPPY GUT® REBOOT: 28-Day Cleanse focuses on restoring all three components of a healthy gut so that you can stop thinking and worrying about your digestion once and for all. Not to mention, when you heal your gut, so many other things get better, like inflammation, brain fog, and fatigue.


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